Application of constrained real-space refinement of flexible molecular fragments to automatic model building of RNA structures

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F12%3A43871551" target="_blank" >RIV/62157124:16370/12:43871551 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1107/S0021889812007546" target="_blank" >http://dx.doi.org/10.1107/S0021889812007546</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1107/S0021889812007546" target="_blank" >10.1107/S0021889812007546</a>

Result language

angličtina

Original language name

Application of constrained real-space refinement of flexible molecular fragments to automatic model building of RNA structures

Original language description

New methods have been developed for locating phosphate groups and nucleic acid bases in the electron density of RNA structures. These methods utilize a constrained real-space refinement of molecular fragments and a phased rotation-conformation-translation function. Real-space refinement has also contributed to the improvement of the bone/base method of RNA model building and to redesigning the method of building double helices in nucleic acid structures. This improvement is reflected in the increased accuracy of the model building and the ability to better distinguish between correct and false solutions. A program, RSR, was created, and the programs NUT, HEL and DHL were upgraded and organized into a program system, which is CCP4 oriented. Source codeswill also be released.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FR - Pharmacology and apothecary chemistry

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Applied Crystallography

ISSN

0021-8898

e-ISSN

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Volume of the periodical

45

Issue of the periodical within the volume

2

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

309-315

UT code for WoS article

000302808300019

EID of the result in the Scopus database

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