Antiurease activity of plants growing in the Czech Republic.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F14%3A43872672" target="_blank" >RIV/62157124:16370/14:43872672 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1080/14786419.2014.888553" target="_blank" >http://dx.doi.org/10.1080/14786419.2014.888553</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/14786419.2014.888553" target="_blank" >10.1080/14786419.2014.888553</a>
Alternative languages
Result language
angličtina
Original language name
Antiurease activity of plants growing in the Czech Republic.
Original language description
The antiurease activity of the aqueous extracts of 42 plants growing in the Czech Republic was investigated. A phenol-hypochlorite reaction was used for the determination of ammonia produced by urease. The inhibitory activity of the extracts at a concentration of 0.2 mg/mL varied from 17.8% to 80.0%. Extracts from six Potentilla species expressed inhibitory activity against jack bean urease. They were further investigated for their phenolic constituents and the major compounds were subjected to molecular docking. The results revealed that both jack bean urease and Helicobacter pylori urease were inhibited by quercetin-3-O-beta-D-galactopyranoside-6?-gallate (1), myricetin-3-O-beta-D-glucuronide (2), tiliroside (3) and B-type procyanidin (4). The antiurease activity of the investigated Potentilla species is probably due to the presence of complex phenolic constituents such as flavonoid glycosides and catechin dimers.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Natural product research
ISSN
1478-6419
e-ISSN
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Volume of the periodical
28
Issue of the periodical within the volume
12
Country of publishing house
GB - UNITED KINGDOM
Number of pages
6
Pages from-to
868-873
UT code for WoS article
000335848500003
EID of the result in the Scopus database
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