The metabolic profile of essential oils and assessment of anti-urease activity by ESI-mass spectrometry of Salvia officinalis L.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F19%3A43877430" target="_blank" >RIV/62157124:16370/19:43877430 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0254629918300796" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0254629918300796</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.sajb.2018.04.023" target="_blank" >10.1016/j.sajb.2018.04.023</a>
Alternative languages
Result language
angličtina
Original language name
The metabolic profile of essential oils and assessment of anti-urease activity by ESI-mass spectrometry of Salvia officinalis L.
Original language description
For decades, the therapeutic benefits of medicinal plants and their biologically active constituents have been well documented. In this study, the metabolic profile of Egyptian Salvia officinalis essential oils using Gas Chromatography (GC) and Gas Chromatography-Mass Spectrometry (GC-MS), total phenolic content (TPC) and anti-enzymatic properties of aqueous extract of S. officinalis (AESO) against jack bean urease (JBU) by an Electrospray Ionization-Mass Spectrometry (ESI-MS) were investigated. The results revealed that the primary metabolites detected in Salvia essential oils were 1,8-cineole (15.4%), oxygenated sesquiterpene viridiflorol (7.1%), nonacosane (3.1%), camphor (3.0%), and pentacosane (2.4%). The TPC content was determined to be 37.1 mg GAE/g dry plant material, while AESO exerted for the first time, anti-JBU with an IC50 value of 1.65 mg/mL. This study presents phenolic-rich AESO as a promising curative agent in the development of urease inhibitors useful to treat diseases induced by urease-producing pathogens.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10611 - Plant sciences, botany
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
South African Journal of Botany
ISSN
0254-6299
e-ISSN
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Volume of the periodical
120
Issue of the periodical within the volume
Jan
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
4
Pages from-to
175-178
UT code for WoS article
000456314600022
EID of the result in the Scopus database
2-s2.0-85047202626