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Influence of concentration and type of microcrystalline cellulose on the physical properties of tablets containing Cornelian cherry fruits

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F17%3A43875605" target="_blank" >RIV/62157124:16370/17:43875605 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1515/acph-2017-0019" target="_blank" >http://dx.doi.org/10.1515/acph-2017-0019</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1515/acph-2017-0019" target="_blank" >10.1515/acph-2017-0019</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Influence of concentration and type of microcrystalline cellulose on the physical properties of tablets containing Cornelian cherry fruits

  • Original language description

    The aim of this study was to find the optimal tablet composition with maximum content of dried fruits (Cornus mas L.). The effect of three different concentrations (12.5, 25 and 50 %) of two types of microcrystalline cellulose (Avicel (R) PH 101 and Avicel (R) PH 200) and three different compression pressures (20, 60 and 100 MPa) on the physical properties of tablet blends and tablets was studied. Tablets containing 50 % Avicel (R) PH 101 compressed under 100 MPa were found to have the best physical properties. This combination of composition and compression pressure resulted in stable tablets even after storage under accelerated stability conditions (6 months, 40 degrees C and 75 % RH).

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30104 - Pharmacology and pharmacy

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Acta pharmaceutica

  • ISSN

    1330-0075

  • e-ISSN

  • Volume of the periodical

    67

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    HR - CROATIA

  • Number of pages

    16

  • Pages from-to

    187-202

  • UT code for WoS article

    000403155900003

  • EID of the result in the Scopus database