Anti-inflammatory Activity of Various Prenylated Phenolic Compounds

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F18%3A43876706" target="_blank" >RIV/62157124:16370/18:43876706 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Anti-inflammatory Activity of Various Prenylated Phenolic Compounds
Original language description
Phenolic compounds can be divided into several categories with the common structural feature of phenolic hydroxyl. Their biological activity is often enhanced by so called prenylation, where the type of the prenyl connection and modification affects the bio-activity. The lecture would shortly summarize the effects of prenylated phenolics in vitro in cellular or biochemical systems on the production and release of inflammation-related cytokines; their effects on the inhibition of cyclooxygenases and lipoxygenases; the effects on the production of nitric oxide, an antiradical and antioxidant activity, and the effect on the inhibition of the release of enzymes and mediators from neutrophils, mast cells and macrophages. Some selected prenylated flavonoids, 2-arylbenzofurans, and stilbenes as potential antiphlogistic substances will be discussed in detail. The information about the antiphlogistic potential of prenylated phenolics gives the idea that a big pool of natural prenylated phenols represents a source of inspiration for synthesis, and that prenylated phenols are active principles of various medicinal plants used to combat inflammation
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
12th International Symposium on Pharmaceutical Sciences: ISOPS 2018 Proceeding Book
ISBN
978-605-136-408-7
ISSN
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e-ISSN
neuvedeno
Number of pages
1
Pages from-to
14
Publisher name
ANKARA UNIV PRESS
Place of publication
Ankara
Event location
Ankara
Event date
Jun 26, 2018
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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