Effect of selected 8-hydroxyquinoline-2-carboxanilides on viability and sulfate metabolism of Desulfovibrio piger

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F18%3A43876761" target="_blank" >RIV/62157124:16370/18:43876761 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14310/18:00102287

Result on the web

<a href="https://www.researchgate.net/publication/323108334_Effect_of_selected_8-hydroxyquinoline-2-carboxanilides_on_viability_and_sulfate_metabolism_of_Desulfovibrio_piger" target="_blank" >https://www.researchgate.net/publication/323108334_Effect_of_selected_8-hydroxyquinoline-2-carboxanilides_on_viability_and_sulfate_metabolism_of_Desulfovibrio_piger</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jab.2018.01.004" target="_blank" >10.1016/j.jab.2018.01.004</a>

Result language

angličtina

Original language name

Effect of selected 8-hydroxyquinoline-2-carboxanilides on viability and sulfate metabolism of Desulfovibrio piger

Original language description

An increased number of sulfate-reducing bacteria is often isolated from faeces of patients with gastrointestinal diseases, which can be the cause of the development of bowel inflammation. Frequent use of antibiotics causes the resistance of intestinal microorganisms and ineffective treatment of these diseases. The antimicrobial activity and biological properties of the selected ring-substituted 8-hydroxyquinoline-2-carboxanilides against Desulfovibrio piger Vib-7 were studied. The addition of these compounds in the cultivation medium inhibited the bacterial growth and the process of sulfate reduction dose-dependently. A significant cytotoxic activity under the influence of ring-substituted 8-hydroxyquinoline-2-carboxanilides was determined. The strongest cytotoxic effect of the derivatives was observed for compounds 8-hydroxy-N-(3-methoxyphenyl)quinoline-2-carboxamide and 8-hydroxy-N-(3-trifluoromethylphenyl)quinoline-2-carboxamide that caused a low survival of D. piger Vib-7 in concentration 17 mu M and high toxicity rates. (C) 2018 Faculty of Health and Social Sciences, University of South Bohemia in Ceske Budejovice. Published by Elsevier Sp. z o.o. All rights reserved.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10606 - Microbiology

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Applied Biomedicine

ISSN

1214-021X

e-ISSN

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Volume of the periodical

16

Issue of the periodical within the volume

3

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

6

Pages from-to

241-246

UT code for WoS article

000440056300012

EID of the result in the Scopus database

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