Summary of numerical analyses for therapeutic uses of laser-activated gold nanoparticles
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18450%2F18%3A50014811" target="_blank" >RIV/62690094:18450/18:50014811 - isvavai.cz</a>
Alternative codes found
RIV/00179906:_____/18:10382625
Result on the web
<a href="https://www.tandfonline.com/doi/full/10.1080/02656736.2018.1440016" target="_blank" >https://www.tandfonline.com/doi/full/10.1080/02656736.2018.1440016</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/02656736.2018.1440016" target="_blank" >10.1080/02656736.2018.1440016</a>
Alternative languages
Result language
angličtina
Original language name
Summary of numerical analyses for therapeutic uses of laser-activated gold nanoparticles
Original language description
The optimal light dose, heat generation, consequent heat spread and an accurate thermal damage model, are key components of effective laser therapies. Recent advances in nanotechnology offer numerous possibilities on how to increase the efficacy of hyperthermia for tumour treatments. Gold nanoparticles are a promising candidate towards the achievement of this goal owing to their properties for efficiently converting light to heat. In this review, we summarise the numerical tools that are available for theoretical studies of gold-nanoparticle-mediated photo-thermal therapy. The processes that occur in the treatments based on light propagation inside biological tissues and the subsequent temperature distributions are considered first, followed by evaluation of the thermal damage. The fundamental ideas underlying the presented methods are described in addition to their applications in photo-thermal therapy and its effects. The descriptions of extensively used tools for the characterisation of nanoparticles across multiple research fields are also presented for estimating the electromagnetic properties of gold nanoparticles (e.g. discrete dipole approximations, finite-difference time-domain simulations), the Monte Carlo model of light propagation in biological tissues, and the Pennes' bio-heat equation. In addition, the Arrhenius damage evaluation and the cumulative effective minutes normalisation methods are described. Finally, recent in vivo and in vitro results from the rapidly growing field of nanomedicine are presented.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)
Result continuities
Project
<a href="/en/project/GA16-13967S" target="_blank" >GA16-13967S: Plasmonic nanoparticles for theranostics with tunable optothermal properties</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
INTERNATIONAL JOURNAL OF HYPERTHERMIA
ISSN
0265-6736
e-ISSN
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Volume of the periodical
34
Issue of the periodical within the volume
8
Country of publishing house
GB - UNITED KINGDOM
Number of pages
10
Pages from-to
1255-1264
UT code for WoS article
000444497400013
EID of the result in the Scopus database
2-s2.0-85053290045