Quantitative Approach to Fish Cytogenetics in the Context of Vertebrate Genome Evolution
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18470%2F21%3A50017946" target="_blank" >RIV/62690094:18470/21:50017946 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.3390/genes12020312" target="_blank" >https://doi.org/10.3390/genes12020312</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/genes12020312" target="_blank" >10.3390/genes12020312</a>
Alternative languages
Result language
angličtina
Original language name
Quantitative Approach to Fish Cytogenetics in the Context of Vertebrate Genome Evolution
Original language description
Our novel Python-based tool EVANGELIST allows the visualization of GC and repeats percentages along chromosomes in sequenced genomes and has enabled us to perform quantitative large-scale analyses on the chromosome level in fish and other vertebrates. This is a different approach from the prevailing analyses, i.e., analyses of GC% in the coding sequences that make up not more than 2% in human. We identified GC content (GC%) elevations in microchromosomes in ancient fish lineages similar to avian microchromosomes and a large variability in the relationship between the chromosome size and their GC% across fish lineages. This raises the question as to what extent does the chromosome size drive GC% as posited by the currently accepted explanation based on the recombination rate. We ascribe the differences found across fishes to varying GC% of repetitive sequences. Generally, our results suggest that the GC% of repeats and proportion of repeats are independent of the chromosome size. This leaves an open space for another mechanism driving the GC evolution in vertebrates.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
GENES
ISSN
2073-4425
e-ISSN
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Volume of the periodical
12
Issue of the periodical within the volume
2
Country of publishing house
CH - SWITZERLAND
Number of pages
16
Pages from-to
"Article Number: 312"
UT code for WoS article
000622561400001
EID of the result in the Scopus database
2-s2.0-85102359058