All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Two frequent polymorphisms of angiotensinogen and their association with multiple sclerosis progression rate

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F11%3A%230001542" target="_blank" >RIV/65269705:_____/11:#0001542 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14740/11:00054011

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.jns.2011.01.020" target="_blank" >http://dx.doi.org/10.1016/j.jns.2011.01.020</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.jns.2011.01.020" target="_blank" >10.1016/j.jns.2011.01.020</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Two frequent polymorphisms of angiotensinogen and their association with multiple sclerosis progression rate

  • Original language description

    A total of 195 patients with multiple sclerosis (MS) and 126 controls were investigated for angiotensinogen/(-6)A/G, M235T/and angiotensin converting enzyme I/D gene polymorphisms to test their association with MS susceptibility and/or disease progression using Global Multiple Sclerosis Severity Score (MSSS). We demonstrated a significant association of M235T polymorphism with MSSS. The MM homozygotes had the lowest (3.8), heterozygotes MT higher (5.2) and homozygotes TT the highest (5.4) mean MSSS values (P = 0.02). For polymorphisms (-6)A/G of ATG, only a trend was observed (P = 0.06), where the homozygotes GG carried lower MSSS values than heterozygotes and homozygotes AA. No significant association with susceptibility was observed. For ACE I/D polymorphism, neither significant differences in the genotype-phenotype study nor in the case-control study were observed.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of the Neurological Sciences

  • ISSN

    0022-510X

  • e-ISSN

  • Volume of the periodical

    303

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    4

  • Pages from-to

    31-34

  • UT code for WoS article

    000289339900004

  • EID of the result in the Scopus database