Ethamsylate (Dicynone (R)) Interference in Determination of Serum Creatinine, Uric Acid, Triglycerides, and Cholesterol in Assays Involving the Trinder Reaction; In Vivo and In Vitro
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F14%3A00061464" target="_blank" >RIV/65269705:_____/14:00061464 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.7754/Clin.Lab.2013.130902" target="_blank" >http://dx.doi.org/10.7754/Clin.Lab.2013.130902</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.7754/Clin.Lab.2013.130902" target="_blank" >10.7754/Clin.Lab.2013.130902</a>
Alternative languages
Result language
angličtina
Original language name
Ethamsylate (Dicynone (R)) Interference in Determination of Serum Creatinine, Uric Acid, Triglycerides, and Cholesterol in Assays Involving the Trinder Reaction; In Vivo and In Vitro
Original language description
Background: The aim of our research was the quantification of interfering properties of the haemostatic drug Dicynone (R) (ethamsylate) in serum creatinine, uric acid, cholesterol, and triglyceride assays using the Trinder reaction. Methods: Blood from patients was collected before and 15 minutes after administration of 500 mg Dicynone (R) dose i.v. and the above mentioned analytes were quantified using Roche assays (Cobas 8000). In our in vitro experiment, we measured concentrations of the analytes inpooled serum aliquots with final concentrations of Dicynone (R) additions 0, 30, 60, 150, and 300 mg/L. Aliquots with 60 mg/L Dicynone (R) were also measured at 2, 6, and 8 hours after initial measurement when stored in 22 degrees C and 4 degrees C for comparison. Results: Concentrations of the measured analytes in samples from patients administered with a 500 mg dose of Dicynone (R) were lower in all cases (n = 10) when compared to values in samples taken immediately before treatment. T
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Clinical Laboratory
ISSN
1433-6510
e-ISSN
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Volume of the periodical
60
Issue of the periodical within the volume
8
Country of publishing house
DE - GERMANY
Number of pages
4
Pages from-to
1373-1376
UT code for WoS article
000342857800015
EID of the result in the Scopus database
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