The Use of Biomarkers in Early Diagnostics of Pancreatic Cancer
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F18%3A00068709" target="_blank" >RIV/65269705:_____/18:00068709 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/18:00103475
Result on the web
<a href="https://www.hindawi.com/journals/cjgh/2018/5389820/" target="_blank" >https://www.hindawi.com/journals/cjgh/2018/5389820/</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2018/5389820" target="_blank" >10.1155/2018/5389820</a>
Alternative languages
Result language
angličtina
Original language name
The Use of Biomarkers in Early Diagnostics of Pancreatic Cancer
Original language description
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid malignancies with increasing incidence. The poor prognosis is due to the aggressive nature of the tumor, late detection, and the resisance to chemotherapy and radiotherapy. A radical surgery procedure is the only treatment that has been shown to improve the 5-year survival rate to 20-25%. However, the majority of patients (80-85%) are diagnosed with locally advanced or metastatic disease and just 15-20% patients are diagnosed in an early stage allowing them to undergo the potentially curatice surgical resection. The early detection of PDAC without the use of invasive methods is challenging and discovery of a cost-effective biomarker with high specifity and sensitivity could significantly improve the treatment and survival in these patients. In this review, we summarize current and newly examined biomarkers in early PDAC detection.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30219 - Gastroenterology and hepatology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Canadian Journal of Gastroenterology and Hepatology
ISSN
2291-2797
e-ISSN
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Volume of the periodical
2018
Issue of the periodical within the volume
AUG 2018
Country of publishing house
GB - UNITED KINGDOM
Number of pages
10
Pages from-to
5389820
UT code for WoS article
000442877300001
EID of the result in the Scopus database
2-s2.0-85052611027