Current trends in the diagnosis of pancreatic cancer
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00098892%3A_____%2F22%3A10157477" target="_blank" >RIV/00098892:_____/22:10157477 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/22:00076383 RIV/00209805:_____/22:00079067 RIV/00216224:14110/22:00126942 RIV/61989592:15110/22:73614785
Result on the web
<a href="https://casopisvnitrnilekarstvi.cz/artkey/vnl-202206-0002_current-trends-in-the-diagnosis-of-pancreatic-cancer.php" target="_blank" >https://casopisvnitrnilekarstvi.cz/artkey/vnl-202206-0002_current-trends-in-the-diagnosis-of-pancreatic-cancer.php</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.36290/vnl.2022.076" target="_blank" >10.36290/vnl.2022.076</a>
Alternative languages
Result language
angličtina
Original language name
Current trends in the diagnosis of pancreatic cancer
Original language description
Pancreatic ductal adenocarcinoma (PDAC) is a dreaded malignancy with a dismal 5-year survival rate despite maximal efforts on optimizing treatment strategies. Currently, early detection is considered to be the most effective way to improve survival as radical resection is the only potential cure. PDAC is often divided into four categories based on the extent of disease: resectable, borderline resectable, locally advanced, and metastatic. Unfortunately, the majority of patients are diagnosed with locally advanced or metastatic disease, which renders them ineligible for curative resection. This is mainly due to the lack of or vague symptoms while the disease is still localized, although appropriate utilization and prompt availability of adequate diagnostic tools is also critical given the aggressive nature of the disease. A cost-effective biomarker with high specificity and sensitivity allowing early detection of PDAC without the need for advanced or invasive methods is still not available. This leaves the diagnosis dependent on radiodiagnostic methods or endoscopic ultrasound. Here we summarize the latest epidemiological data, risk factors, clinical manifestation, and current diagnostic trends and implications of PDAC focusing on serum biomarkers and imaging modalities. Additionally, up-to-date management and therapeutic algorithms are outlined.
Czech name
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Czech description
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Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
30219 - Gastroenterology and hepatology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Vnitřní lékařství
ISSN
0042-773X
e-ISSN
1801-7592
Volume of the periodical
68
Issue of the periodical within the volume
6
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
8
Pages from-to
363-370
UT code for WoS article
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EID of the result in the Scopus database
2-s2.0-85139753435