Residual neuromuscular block in paediatric anaesthesia
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F19%3A00070512" target="_blank" >RIV/65269705:_____/19:00070512 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/19:00109048
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0007091218307670?via%3Dihub#" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0007091218307670?via%3Dihub#</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.bja.2018.10.001" target="_blank" >10.1016/j.bja.2018.10.001</a>
Alternative languages
Result language
angličtina
Original language name
Residual neuromuscular block in paediatric anaesthesia
Original language description
Background: Residual neuromuscular blockade (RNB) in postoperative period is frequent (26-88%) and it is associated with negative impact on perioperative morbidity. The safety cut-off measured by accelerometry is currently defined as Train-of-four ratio (TOFr) >= 0.9. The primary outcome of the study was detect the incidence of RNB measured just prior extubation in the operating room (OR) (according to pragmatic trial design) and the secondary outcome was the incidence of the RNB in postanaethesia care unit (PACU). Methods: After Ethics Committee (10/2016) approval, paediatric patients (1.1.2017-31.12.2017) undergoing surgery in general anaesthesia with muscle relaxation were included in the study. The level of blockade was measured just prior to extubation in OR (patient eligible for extubation according to the anesthesiologist) and after arrival at PACU with acceleromtery - TOF-Watch(R)SX (Organon, Inc, West Orange, NJ). The mode for measurement was Train-of-four (TOF) and Train-of-four ratio (TOFr), in case of deep blockade Post-tetanic count (PTC). Data are described by descriptive analytic methods (mean, standard deviation -SD, median). Results: Overall, 291 patients were included in the study. The incidence of RNB in the OR was 48.2 % (95% CI: 42.4 54.1%, n=136) and the incidence of RNB in PACU was 26.9 % (95% CI: 19.5 35.3 %, n = 32). Active block reversal was administered in 23.3% (n=68) patients. Overall, 31.6% (87/275) patients were extubated with TOFr<0.9. Conclusion: Residual neuromuscular blockade in selected cohort of paediatric patients was frequent.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30223 - Anaesthesiology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
British Journal Of Anaesthesia
ISSN
0007-0912
e-ISSN
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Volume of the periodical
122
Issue of the periodical within the volume
1
Country of publishing house
GB - UNITED KINGDOM
Number of pages
2
Pages from-to
"E1"-"E2"
UT code for WoS article
000453927600001
EID of the result in the Scopus database
2-s2.0-85058663537