Quantitative myotonia assessment with a commercially available dynamometer in myotonic dystrophy types 1 and 2
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F19%3A00070531" target="_blank" >RIV/65269705:_____/19:00070531 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/19:00109475
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/full/10.1002/mus.26401" target="_blank" >https://onlinelibrary.wiley.com/doi/full/10.1002/mus.26401</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/mus.26401" target="_blank" >10.1002/mus.26401</a>
Alternative languages
Result language
angličtina
Original language name
Quantitative myotonia assessment with a commercially available dynamometer in myotonic dystrophy types 1 and 2
Original language description
Introduction: The objective of this study was to develop a simple method for quantitative assessment of myotonia in patients with myotonic dystrophy type 1 (DM1) and DM2, to compare the myotonia severity, and to correlate this objective outcome with a subjective scale, the Myotonia Behaviour Scale (MBS). Methods: A commercially available dynamometer was used for all measurements. The relaxation time after voluntary contraction was measured in 20 patients with DM1, 25 patients with DM2, and 35 healthy controls. Results: The average relaxation time was 0.17 s in controls, 2.96 s in patients with DM1, and 0.4 s in patients with DM2. The correlation between relaxation time and MBS score was significant, 0.627 in patients with DM1 and 0.581 in patients with DM2. Discussion: Our method provides a valid and reliable quantitative measure of grip myotonia suitable as an outcome measure in clinical trials and as part of routine examinations to gather data on the natural history of myotonic disorders.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30210 - Clinical neurology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Muscle and Nerve
ISSN
0148-639X
e-ISSN
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Volume of the periodical
59
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
431-435
UT code for WoS article
000461232700012
EID of the result in the Scopus database
2-s2.0-85059669691