Real-world evaluation of UK high hyperdiploidy profile using a large cohort of patients provided by HARMONY data platform
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F23%3A00078417" target="_blank" >RIV/65269705:_____/23:00078417 - isvavai.cz</a>
Result on the web
<a href="https://www.nature.com/articles/s41375-023-02046-0" target="_blank" >https://www.nature.com/articles/s41375-023-02046-0</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41375-023-02046-0" target="_blank" >10.1038/s41375-023-02046-0</a>
Alternative languages
Result language
angličtina
Original language name
Real-world evaluation of UK high hyperdiploidy profile using a large cohort of patients provided by HARMONY data platform
Original language description
The most common genetic abnormality in childhood acute lymphoblastic leukaemia (ALL) is high hyperdiploidy (HeH), accounting for 30-35% of B-cell precursor ALL cases [1]. HeH is the non-random gain of chromosomes, resulting the modal chromosome number to be between 51 and 65 (or 67) [2,3,4]. Multiple studies have associated HeH with good outcome [1, 5, 6], however, the high frequency of HeH group resulted in accounting for up to 25% of all relapses in childhood ALL [7]. Therefore, identification of robust risk factors within this group is essential.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
30205 - Hematology
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Leukemia
ISSN
0887-6924
e-ISSN
1476-5551
Volume of the periodical
37
Issue of the periodical within the volume
12
Country of publishing house
GB - UNITED KINGDOM
Number of pages
4
Pages from-to
2493-2496
UT code for WoS article
001075364700002
EID of the result in the Scopus database
2-s2.0-85173001028