Vagus nerve stimulation as immunomodulatory therapy for stroke: A comprehensive review
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F24%3A00079143" target="_blank" >RIV/65269705:_____/24:00079143 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/24:00139928
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0014488623003138?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0014488623003138?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.expneurol.2023.114628" target="_blank" >10.1016/j.expneurol.2023.114628</a>
Alternative languages
Result language
angličtina
Original language name
Vagus nerve stimulation as immunomodulatory therapy for stroke: A comprehensive review
Original language description
Stroke is a devastating cerebrovascular pathology with high morbidity and mortality. Inflammation plays a central role in the pathophysiology of stroke. Vagus nerve stimulation (VNS) is a promising immunomodulatory method that has shown positive effects in stroke treatment, including neuroprotection, anti-apoptosis, antiinflammation, antioxidation, reduced infarct volume, improved neurological scores, and promotion of M2 microglial polarization. In this review, we summarize the current knowledge about the vagus nerve's immunomodulatory effects through the cholinergic anti-inflammatory pathway (CAP) and provide a comprehensive assessment of the available experimental literature focusing on the use of VNS in stroke treatment.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30103 - Neurosciences (including psychophysiology)
Result continuities
Project
<a href="/en/project/NU23-04-00382" target="_blank" >NU23-04-00382: Proteomic identification of biomarkers associated with IL-6 variability in aneurysmal subarachnoid hemorrhage</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Experimental neurology
ISSN
0014-4886
e-ISSN
1090-2430
Volume of the periodical
372
Issue of the periodical within the volume
FEB 2024
Country of publishing house
US - UNITED STATES
Number of pages
12
Pages from-to
114628
UT code for WoS article
001135087500001
EID of the result in the Scopus database
2-s2.0-85179076567