Development of autonomic heart rate modulations during childhood and adolescence

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F24%3A00080252" target="_blank" >RIV/65269705:_____/24:00080252 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/24:00136329

Result on the web

<a href="https://link.springer.com/article/10.1007/s00424-024-02979-0" target="_blank" >https://link.springer.com/article/10.1007/s00424-024-02979-0</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00424-024-02979-0" target="_blank" >10.1007/s00424-024-02979-0</a>

Result language

angličtina

Original language name

Development of autonomic heart rate modulations during childhood and adolescence

Original language description

Autonomic control of heart rate is well known in adult subjects, but limited data are available on the development of the heart rate control during childhood and adolescence. Continuous 12-lead electrocardiograms were recorded in 1045 healthy children and adolescents (550 females) aged 4 to 19 years during postural manoeuvres involving repeated 10-min supine, unsupported sitting, and unsupported standing positions. In each position, heart rate was measured, and heart rate variability indices were evaluated (SDNN, RMSSD, and high (HF) and low (LF) frequency components were obtained). Quasi-normalized HF frequency components were defined as qnHF = HF/(HF + LF). These measurements were, among others, related to age using linear regressions. In supine position, heart rate decreases per year of age were significant in both sexes but lower in females than in males. In standing position, these decreases per year of age were substantially lowered. RMSSD and qnHF indices were independent of age in supine position but significantly decreased with age in sitting and standing positions. Correspondingly, LF/HF proportions showed steep increases with age in sitting and standing positions but not in the supine position. The study suggests that baseline supine parasympathetic influence shows little developmental changes during childhood and adolescence but that in young children, sympathetic branch is less responsive to vagal influence. While vagal influences modulate cardiac periods in young and older children equally, they are less able to suppress the sympathetic influence in younger children.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30105 - Physiology (including cytology)

Project

<a href="/en/project/NV19-02-00197" target="_blank" >NV19-02-00197: Autonomic provocations for the assessment of cardiac repolarization dynamics in children and the progression of sex-related differences in adolescents.</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Pflügers Archiv European Journal of Physiology

ISSN

0031-6768

e-ISSN

1432-2013

Volume of the periodical

476

Issue of the periodical within the volume

8

Country of publishing house

DE - GERMANY

Number of pages

21

Pages from-to

1187-1207

UT code for WoS article

001257044400001

EID of the result in the Scopus database

2-s2.0-85197420198