Analysis of a Model Reduction Method (D-QSSA) applied to a Class of Biochemical Networks

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985556%3A_____%2F21%3A00546360" target="_blank" >RIV/67985556:_____/21:00546360 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S2405896321017225" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2405896321017225</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ifacol.2021.10.317" target="_blank" >10.1016/j.ifacol.2021.10.317</a>

Result language
angličtina
Original language name
Analysis of a Model Reduction Method (D-QSSA) applied to a Class of Biochemical Networks
Original language description
This paper is aimed to develop and test one novel and unexplored enhancement of the classical model reduction method applied to a class of biochemical networks. Both methods, being (i) the standard quasi-steady-state approximation (QSSA), and (ii) the so-called delayed-QSSA methods are extensively presented. Specially, the numerical issues related to the setting of constant delays are discussed. Finally, for one slightly modi ed version of an enzymesubstrate reaction network (Michaelis-Menten kinetics), the comparison of the full non-reduced system behavior with respective variants of reduced model is presented and future prospects arenproposed.
Czech name
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Czech description
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Project
<a href="/en/project/GA19-05872S" target="_blank" >GA19-05872S: Synchronization and decentralized control of complex networks</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
IFAC-PapersOnLine.Volume 54, Issue 15 - 11th IFAC Symposium on Biological and Medical Systems BMS 2021
ISBN
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ISSN
2405-8963
e-ISSN
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Number of pages
6
Pages from-to
568-573
Publisher name
Elsevier
Place of publication
Amsterdam
Event location
Ghent
Event date
Sep 19, 2021
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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