Dipeptidyl peptidase-IV activity and/or structure homologues (DASH) in transformed neuroectodermal cells.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F03%3A20030149" target="_blank" >RIV/67985823:_____/03:20030149 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Dipeptidyl peptidase-IV activity and/or structure homologues (DASH) in transformed neuroectodermal cells.
Original language description
DASH molecules (DPP-IV activity and/or structure-homologues) expression pattern in glioma and melanoma cells depends on cell type and changes during transition from the proliferation to the quiescent stage of growth. Changes in the spectrum of DASH molecules may shift substrate preferences and result in modified response of cell to the signals carried by biologically active DASH substrates. Inhibitors of DPP-IV-like enzymatic activity are expected to be of a significant therapeutic value in the treatment of HIV infection, diabetes mellitus and as immunosuppressants in the transplantation surgery and autoimmune diseases, including multiple sclerosis.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA301%2F02%2F0962" target="_blank" >GA301/02/0962: Role of Dipeptidyl Peptidase IV-like Molecules in the Regulation of Growth Properties of Transformed Neuroectodermal Cells</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2003
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Advances in Experimental Medicine and Biology
ISSN
0065-2598
e-ISSN
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Volume of the periodical
524
Issue of the periodical within the volume
N/A
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
95-102
UT code for WoS article
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EID of the result in the Scopus database
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