Does Cd36 gene play a key role in disturbed glucose and fatty acid metabolism in Prague hypertensive hypertriglyceridemic rats?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F04%3A00102531" target="_blank" >RIV/67985823:_____/04:00102531 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Does Cd36 gene play a key role in disturbed glucose and fatty acid metabolism in Prague hypertensive hypertriglyceridemic rats?

Original language description

The polymorphism of Cd36 gene in Prague hypertriglyceridemic (HTG) rat was investigated in order to compare this strain with spontaneously hypertensive rats (SHR). In spite of the fact that HTG and SHR had similar metabolic abnormalities, Cd36 mutation characteristic for SHR was absent in HTG strain. It is evident that genes other than Cd36 play an important role in pathogenesis of metabolic syndrome of HTG rats

Czech name

Hraje gen Cd36 klíčovou úlohu při poruchách metabolismu glukózy a mastných kyselin u Pražského hypertenzního hypertriglyceridemického potkana?

Czech description

Studovali jsme polymorfismus genu Cd36 u Pražského hypertriglyceridemického potkana (HTG) pro srovnání tohoto kmenu se spontánně hypertenzními potkany (SHR). Navzdory tomu, že HTG a SHR mají podobné metabolické abnormality, mutace Cd36, charakteristickápro SHR, chyběla u HTG kmene. Není pochyb o tom, že důležitou úlohu v patogenezi metabolického syndromu HTG potkanů hrají jiné geny než je CD36

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2004

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Physiological Research

ISSN

0862-8408

e-ISSN

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Volume of the periodical

53

Issue of the periodical within the volume

3

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

7

Pages from-to

265-271

UT code for WoS article

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EID of the result in the Scopus database

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