Vascular endothelial cells in cultures on metal/C:H composite films
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F04%3A00104205" target="_blank" >RIV/67985823:_____/04:00104205 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Vascular endothelial cells in cultures on metal/C:H composite films
Original language description
Adhesion, proliferation and maturation of vascular endothelial cells in cultures derived from the bovine pulmonary artery (line CPAE) were studied on Ti/C:H or Ag/C:H films prepared on glass using dc magnetron plasma deposition. The concentration of Ti or Ag in the films ranged from 0% to 20%. On Ag/C:H layers, increasing concentration of silver markedly decreased cell viability. Only samples with very low silver content allowed cell spreading and formation of continuous endothelial layer. Although long-term presence of this material in patient´s organism would not be advantageous, antimicrobial effect of silver may be favorable for short term applications, e.g. coating of catheters. On Ti/C:H layers, the cells were similarly or more active in adhesion, proliferation and maturation than those on glass or pure amorphous carbon, respectively.
Czech name
Cévní endotelové buňky v kulturách na kompozitních vrstvách z kovů a amorfního uhlíku
Czech description
Byla studována adhese, růst a vyzrávání cévních endotelových buněk linie CPAE na vrstvách Ti/C:H or Ag/C:H (koncentrace obou kovů od 0% do 20%) deponovaných na mikroskopických podložních sklech pomocí dc magnetronu. Se stoupající koncentrací stříbra výrazně klesala životaschopnost buněk. Pouze nejnižší koncentrace stříbra blízké 0 umožnily vytvoření souvislé endotelové vrstvy. Naproti tomu titan příznivě ovlivnil adhesi, růst a vyzrávání endotelových buněk
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EI - Biotechnology and bionics
OECD FORD branch
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Result continuities
Project
<a href="/en/project/OC%20527.130" target="_blank" >OC 527.130: In vitro biocompatibility and antimicrobial properties of biofunctional substrates coated with hard hydrocarbon polymer composite layers</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2004
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Engineering of Biomaterials
ISSN
1429-7248
e-ISSN
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Volume of the periodical
7
Issue of the periodical within the volume
37
Country of publishing house
PL - POLAND
Number of pages
3
Pages from-to
18-20
UT code for WoS article
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EID of the result in the Scopus database
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