A new transgenic rat model of hepatic steatosis and the metabolic syndrome
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F05%3A00001032" target="_blank" >RIV/67985823:_____/05:00001032 - isvavai.cz</a>
Alternative codes found
RIV/00023001:_____/05:00000307
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
A new transgenic rat model of hepatic steatosis and the metabolic syndrome
Original language description
Fatty liver is extremely common in insulin resistant patients with either obesity or lipodystrophy and it has been proposed that hepatic steatosis be considered an additional feature of the metabolic syndrome. We sought to create a new non-obese, rat model with hypertension, hepatic steatosis and the metabolic syndrome by transgenic overexpression of a sterol regulatory element binding protein (SREBP-1a) in the spontaneously hypertensive rat (SHR)
Czech name
Nový transgenní model hepatické steatózy a metabolického syndromu
Czech description
Jaterní steatóza je častá u pacientů s metabolickým syndromem. Pro analýzu patogeneze jaterní steatózy jsme vytvořili nový model pomocí transgenní exprese lidského genu pro Srebp1a (sterol regulatory element binding protein 1a) na genetickém pozadí spontánně hypertenzních potkanů kmene SHR
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2005
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Hypertension
ISSN
0194-911X
e-ISSN
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Volume of the periodical
45
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
1004-1011
UT code for WoS article
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EID of the result in the Scopus database
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