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Sex differences in connexin-43 expression in left ventricles of aging rats

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F05%3A00025098" target="_blank" >RIV/67985823:_____/05:00025098 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Sex differences in connexin-43 expression in left ventricles of aging rats

  • Original language description

    We have found no significant differences in Cx43 expression and phosphorylation between T4-treated and control untreated animals. However, expression of Cx43 was significantly higher in female compared to male rats. We conclude that T4 administration hasno effect on Cx43 expression, but there are sex-dependent differences in Cx43 expression in the left ventricles between aging male and female rats. This can contribute to the higher resistance of females to heart damage

  • Czech name

    Pohlavní rozdíly v obsahu connexinu-43 v levé komoře starých potkanů

  • Czech description

    Zatímco aplikace tyroxinu neměla vliv na obsah connexinu-43, exprese Cx-43 byla signifikantně vyšší u samic než u samců starých potkanů. Zjištěný nález je ve shodě s vyšší resistencí samic na srdeční poškození

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA304%2F05%2F0327" target="_blank" >GA304/05/0327: Influence of thyroid hormones on expression of myofibrillar and Ca2+ transporting proteins</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2005

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Physiological Research

  • ISSN

    0862-8408

  • e-ISSN

  • Volume of the periodical

    54

  • Issue of the periodical within the volume

    6

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    4

  • Pages from-to

    705-708

  • UT code for WoS article

  • EID of the result in the Scopus database