Sex differences in connexin-43 expression in left ventricles of aging rats
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F05%3A00025098" target="_blank" >RIV/67985823:_____/05:00025098 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Sex differences in connexin-43 expression in left ventricles of aging rats
Original language description
We have found no significant differences in Cx43 expression and phosphorylation between T4-treated and control untreated animals. However, expression of Cx43 was significantly higher in female compared to male rats. We conclude that T4 administration hasno effect on Cx43 expression, but there are sex-dependent differences in Cx43 expression in the left ventricles between aging male and female rats. This can contribute to the higher resistance of females to heart damage
Czech name
Pohlavní rozdíly v obsahu connexinu-43 v levé komoře starých potkanů
Czech description
Zatímco aplikace tyroxinu neměla vliv na obsah connexinu-43, exprese Cx-43 byla signifikantně vyšší u samic než u samců starých potkanů. Zjištěný nález je ve shodě s vyšší resistencí samic na srdeční poškození
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA304%2F05%2F0327" target="_blank" >GA304/05/0327: Influence of thyroid hormones on expression of myofibrillar and Ca2+ transporting proteins</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2005
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Physiological Research
ISSN
0862-8408
e-ISSN
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Volume of the periodical
54
Issue of the periodical within the volume
6
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
4
Pages from-to
705-708
UT code for WoS article
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EID of the result in the Scopus database
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