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Fat-specific transgenic expression of resistin in the spontaneously hypertensive rat impairs fatty acid re-esterification

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F06%3A00040435" target="_blank" >RIV/67985823:_____/06:00040435 - isvavai.cz</a>

  • Alternative codes found

    RIV/60461373:22330/06:00017223 RIV/00023001:_____/06:00000697

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Fat-specific transgenic expression of resistin in the spontaneously hypertensive rat impairs fatty acid re-esterification

  • Original language description

    A moderate expression of transgenic resistin in adipose tissue in the SHR was associated with significantly increased FFA/glycerol ratio during adrenaline stimulated lipolysis. Transgenic SHR also exhibited a significant decrease in FFA reesterificationin adipose tissue. These findings raise the possibility that the prodiabetic effects of transgenic resistin may be partly mediated by increased FFA release from adipose tissue due to impaired FFA reesterification in adipocytes

  • Czech name

    Transgenní exprese resistinu v tukové tkáni spontánně hypertenzních potkanů redukuje reesterifikaci mastných kyselin

  • Czech description

    Exprese transgenního resistinu v tukové tkáni SHR potkanů byla asociována s významným zvýšením poměru NEMK/glycerol při adrenalinem stimulované lipolýze. Transgenní SHR potkani měli významně redukovanou reesterifikaci NEMK v tukové tkáni. Tyto výsledky naznačují, že by prodiabetické účinky transgenního resistinu mohly být částečně zprostředkovány zvýšenou sekrecí NEMK z tukové tkáně v důsledku redukované reesterifikace NEMK v adipocytech

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    International Journal of Obesity

  • ISSN

    0307-0565

  • e-ISSN

  • Volume of the periodical

    30

  • Issue of the periodical within the volume

    7

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    3

  • Pages from-to

    1157-1159

  • UT code for WoS article

  • EID of the result in the Scopus database