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Anticonvulsant action of allopregnanolone in immature rats

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F06%3A00040574" target="_blank" >RIV/67985823:_____/06:00040574 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Anticonvulsant action of allopregnanolone in immature rats

  • Original language description

    Allopregnanolone, a metabolite of progesterone, suppresses generalized tonic-clonic seizures elicited by pentetrazol in adult as well as developing rats but it also elicits unwanted effects on motor performance. These effects last longer in rat pups thanin adult rats

  • Czech name

    Anticonvulsivní aktivita allopregnanolonu u nezralých potkanů

  • Czech description

    Allopregnanolon, metabolit progesteronu, potlačuje generalizované tonicko-klonické záchvaty vyvolané pentetrazolem u dospělých i mladých potkanů, ale vyvolává i nežádoucí účinky na motoriku. Tyto účinky trvají déle u mláďat než u dospělých zvířat

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/IBS5011007" target="_blank" >IBS5011007: Synthesis and evaluation of neurosteroids as possible antiepileptics</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Epilepsy Research

  • ISSN

    0920-1211

  • e-ISSN

  • Volume of the periodical

    70

  • Issue of the periodical within the volume

    2-3

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    8

  • Pages from-to

    110-117

  • UT code for WoS article

  • EID of the result in the Scopus database