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The transcriptional repressor REST is a critical regulator of the neurosecretory phenotype

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F06%3A00041831" target="_blank" >RIV/67985823:_____/06:00041831 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    The transcriptional repressor REST is a critical regulator of the neurosecretory phenotype

  • Original language description

    Regulated secretory pathway is fundamental feature of all higher eukaryots. Experiments on PC12 cells demonstrated that transcriptional factor REST directly regulates expression of many genes codin for proteins that are important components of regulatedsecretory pathway

  • Czech name

    Transkripční represor REST je kritickým regulátorem neurosekrečního fenotypu

  • Czech description

    Regulovaná sekrece je základní vlastností eukaryotních buněk. Pokusy na buňkách PC12 ukázaly, že jediný transkripční regulátor REST ovlivňuje přímo expresi několika genů, jejichž produkty patří k důležitým součástem regulované sekrece

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/IAA5011206" target="_blank" >IAA5011206: Influence of oxidative stress on cholinergic neurones and ways of their protection</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Neurochemistry

  • ISSN

    0022-3042

  • e-ISSN

  • Volume of the periodical

    98

  • Issue of the periodical within the volume

    6

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    13

  • Pages from-to

    1828-1840

  • UT code for WoS article

  • EID of the result in the Scopus database