Spironolactone differently influences remodeling of the left ventricle and aorta in L-NAME-induced hypertension

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F07%3A00095729" target="_blank" >RIV/67985823:_____/07:00095729 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Spironolactone differently influences remodeling of the left ventricle and aorta in L-NAME-induced hypertension

Original language description

The aldosterone receptor antagonist spironolactone improved NO production and partially prevented hypertension and LVH development without preventing hypertrophy of aorta in NO-deficient hypertension. The reactive growth of the heart and aorta seems to be controlled by different mechanisms in L-NAME-induced hypertension

Czech name

Spironolakton ovlivňuje odlišně remodelaci levé komory a aorty u L-NAME-indukované hypertenze

Czech description

Antagonista aldosteronového receptoru spironolakton zlepšuje produkci oxidu dusnatého a částečně brání rozvoji hypertenze a hypertrofie levé srdeční komory (nikoliv však aorty) u NO-deficitní hypertenze. Růst srdce a aorty se u L-NAME hypertenze zdá býtkontrolován odlišnými mechanismy

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2007

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Physiological Research

ISSN

0862-8408

e-ISSN

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Volume of the periodical

56

Issue of the periodical within the volume

Suppl.2

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

8

Pages from-to

"S25"-"S32"

UT code for WoS article

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EID of the result in the Scopus database

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