Hypoxia-induced changes of seizure susceptibility in immature rats are modified by vigabatrin

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F07%3A00098023" target="_blank" >RIV/67985823:_____/07:00098023 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Hypoxia-induced changes of seizure susceptibility in immature rats are modified by vigabatrin

Original language description

Exposure of 25-day-old rats to hypobaric hypoxia resulted in an increased susceptibility to pentetrazol-induced seizures and increased mortality 3 days after exposure. Vigabatrin was able to decrease moderately both these effects

Czech name

Vigabatrin modifikuje změny záchvatové vnímavosti vyvolané hypoxií u mláďat potkana

Czech description

Potkani ve věku 25 dnů vykazují 3 dny po exposici hypobarické hypoxie zvýšenou citlivost na záchvatyvyvolané pentetrazolem a zvýšenou mortalitu. Vigabatrin mírně (ale statisticky významně) oslaboval tyto účinky

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

ED - Physiology

OECD FORD branch

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Project

<a href="/en/project/GA304%2F05%2F2582" target="_blank" >GA304/05/2582: Alteration of the neocortical GABAergic system as a consequence of status epilepticus induced at different stages of postnatal development</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2007

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Epileptic Disorders

ISSN

1294-9361

e-ISSN

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Volume of the periodical

10

Issue of the periodical within the volume

Suppl.1

Country of publishing house

FR - FRANCE

Number of pages

8

Pages from-to

37-44

UT code for WoS article

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EID of the result in the Scopus database

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