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Muscarinic Transmission is Impaired in Zouny Adult Transgenic APPswe/PS1dE9 Female Mice

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F07%3A00311242" target="_blank" >RIV/67985823:_____/07:00311242 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Muscarinic Transmission is Impaired in Zouny Adult Transgenic APPswe/PS1dE9 Female Mice

  • Original language description

    We have investigated cholinergic neurotransmission markers in young adult and aged APPswe/PS1dE9 female mice. We found both age and transgen dependent changes. The most important change is impairment of muscarinic receptor-mediated signaling in young transgenic mice

  • Czech name

    Muskarinová neurotransmise je zhoršena u mladých dospělých samic APPswe/PS1dE9 myši

  • Czech description

    Sledovali jsme markery cholinergní neurotransmise samic mladých dospělých a starých APPswe/PS1dE9 myší. Našli jsme změny závislé jak na věku tak i na přítomnosti transgenu. Zvláště závažné je narušení přenosu signálu mezi muskarinovými receptory a G-proteiny

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2007

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    New Trends in Alzenheimer and Parkinson Related Disorders

  • ISBN

    978-88-7587-405-6

  • ISSN

  • e-ISSN

  • Number of pages

    4

  • Pages from-to

  • Publisher name

    Mediamond

  • Place of publication

    Bologna

  • Event location

    Salzburg

  • Event date

    Mar 14, 2007

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article