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Anticonvulsant action of GABA-B receptor agonist SKF97541 Differs from that of Baclofen

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F08%3A00319206" target="_blank" >RIV/67985823:_____/08:00319206 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Anticonvulsant action of GABA-B receptor agonist SKF97541 Differs from that of Baclofen

  • Original language description

    GABA-B receptor agonist SKF97541 exhibits anticonvulsant action against the tonic phase of generalized tonic-clonic seizures elicited by pentetrazol especially in young rats. In contrast to baclofen it does not have mixed anti- and proconvulsant effectsin immature rats

  • Czech name

    Antikonvulsivní účinky agonisty GABA-B receptoru SKF97541 se liší od účinků baklofenu

  • Czech description

    Agonista GABA-B receptorů SKF97541 potlačuje tonickou fázi generalizovaných tonicko-klonických záchvatů vyvolaných pentetrazolem u mláďat potkana. Na rozdíl od baklofenu nemá u nezralých potkanů smíšené anti= a prokonvulsivní účinky

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA305%2F05%2F2581" target="_blank" >GA305/05/2581: Developmental pharmakology of GABA-B systém: its role in epilepsy,cognition and pain</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Physiological Research

  • ISSN

    0862-8408

  • e-ISSN

  • Volume of the periodical

    57

  • Issue of the periodical within the volume

    5

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    4

  • Pages from-to

  • UT code for WoS article

    260893500017

  • EID of the result in the Scopus database