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Xanomeline binding to and activation of muscarinic receptors

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F09%3A00339422" target="_blank" >RIV/67985823:_____/09:00339422 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Xanomeline binding to and activation of muscarinic receptors

  • Original language description

    Xanomeline binds reversibly to orthosteric binding site and irreversibly to another site of all subtypes of muscarinic receptors. In acute functional assays stimulates only M1/M4 subtypes. We demonstrated that irreversibly bound xanomeline also stimulates M2 receptors in cerebral cortex tissue

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    FH - Neurology, neuro-surgery, nuero-sciences

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    New trends in Alzheimer and Parkinson Related Disorders: ADPD 2009

  • ISBN

    978-88-7587-528-2

  • ISSN

  • e-ISSN

  • Number of pages

    4

  • Pages from-to

  • Publisher name

    Medimond

  • Place of publication

    Pianoro

  • Event location

    Praha

  • Event date

    May 11, 2009

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article