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Influence of calcium-dependent potassium channel blockade and nitric oxide inhibition on norepinephrine-induced contractions in two forms of genetic hypertension

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F10%3A00345854" target="_blank" >RIV/67985823:_____/10:00345854 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Influence of calcium-dependent potassium channel blockade and nitric oxide inhibition on norepinephrine-induced contractions in two forms of genetic hypertension

  • Original language description

    The activation of Ca2+-dependent K+ channels (BKCa) leads to the attenuation of vascular contraction. Our study aimed to evaluate BKCa influence on norepinephrine (NE)-induced femoral artery contraction in two forms of genetic hypertension. NO-dependentattenuation of NE-induced contractions was greater in SHR than HTG or Wistar vessels, whereas large conductance Ca2+-dependent K+ channels may play a greater role in modulating vascular contraction in the severe form of hypertension

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/IAA500110902" target="_blank" >IAA500110902: Neurohumoral control of calcium influx: nifedipine-sensitive component of blood pressure in experimental hypertension</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of the American Society of Hypertension

  • ISSN

    1933-1711

  • e-ISSN

  • Volume of the periodical

    4

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    7

  • Pages from-to

  • UT code for WoS article

    278115200004

  • EID of the result in the Scopus database