Contribution of Ca2+-Dependent Cl- Channels to Norepinephrine-Induced Contraction of Femoral Artery Is Replaced by Increasing EDCF Contribution during Ageing
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F14%3A00428048" target="_blank" >RIV/67985823:_____/14:00428048 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1155/2014/289361" target="_blank" >http://dx.doi.org/10.1155/2014/289361</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2014/289361" target="_blank" >10.1155/2014/289361</a>
Alternative languages
Result language
angličtina
Original language name
Contribution of Ca2+-Dependent Cl- Channels to Norepinephrine-Induced Contraction of Femoral Artery Is Replaced by Increasing EDCF Contribution during Ageing
Original language description
The activation of calcium-dependent chloride channels during norepinephrine-induced contraction of vascular smooth muscle was suggested to depolarize cell membrane and to increase calcium entry. Hypertension and ageing are associated with altered calciumhandling including possible activation of calcium-dependent chloride channels. Our study was aimed to determine calcium -dependent chloride channels contribution to norepinephrine-induced contraction during hypertension and ageing. We have found that contribution of calcium -dependent chloride channels to norepinephrine-induced contraction diminished with age, hypertension development, and/or NO synthesis inhibition
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GAP304%2F12%2F0259" target="_blank" >GAP304/12/0259: Mutual interactions of various vasoactive systems, reactive oxygen species and G proteins in experimental hypertension</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
BioMed Research International
ISSN
2314-6133
e-ISSN
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Volume of the periodical
2014
Issue of the periodical within the volume
2014
Country of publishing house
US - UNITED STATES
Number of pages
9
Pages from-to
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UT code for WoS article
000332565500001
EID of the result in the Scopus database
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