Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F11%3A00364489" target="_blank" >RIV/67985823:_____/11:00364489 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s00125-011-2233-2" target="_blank" >http://dx.doi.org/10.1007/s00125-011-2233-2</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00125-011-2233-2" target="_blank" >10.1007/s00125-011-2233-2</a>

Result language
angličtina
Original language name
Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids
Original language description
White adipose tissue plays an active role in the amelioration of obesity and the improvement of glucose homeostasis by combining LC n-3 PUFA intake and calorie restriction in mice fed high-fat diet. Specifically in the epididymal fat in the abdomen, butnot in other fat depots, synergistic induction of mitochondrial oxidative capacity and lipid catabolism was observed, resulting in increased oxidation of metabolic fuels in the absence of mitochondrial uncoupling, while low-grade inflammation was suppressed, reflecting changes in tissue levels of anti-inflammatory lipid mediators, namely 15-Deoxy-12,15-prostaglandin J2 and protectin D1
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FB - Endocrinology, diabetology, metabolism, nutrition
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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