The role of sympathetic nervous system in the development of neurogenic pulmonary edema in spinal cord-injured rats
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F12%3A00376805" target="_blank" >RIV/67985823:_____/12:00376805 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1152/japplphysiol.00574.2011" target="_blank" >http://dx.doi.org/10.1152/japplphysiol.00574.2011</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1152/japplphysiol.00574.2011" target="_blank" >10.1152/japplphysiol.00574.2011</a>
Alternative languages
Result language
angličtina
Original language name
The role of sympathetic nervous system in the development of neurogenic pulmonary edema in spinal cord-injured rats
Original language description
We examined whether the development of neurogenic pulmonary edema (NPE) in rats with balloon compression of spinal cord is a consequence of rapid activation of spinal pathways leading to sympathetic venoconstriction, blood pressure rise, and reflex bradycardia. We demonstrated that considerable activation of thoracic spinal pathways, followed by marked catecholamine secretion, play a major role in the development of NPE in spinal cord-injured rats. Enhanced ?-adrenergic nifedipine-sensitive vasoconstriction is responsible for observed blood pressure changes, subsequent baroreflex bradycardia, and blood volume redistribution, which represent major pathogenetic mechanisms of NPE development
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
—
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Applied Physiology
ISSN
8750-7587
e-ISSN
—
Volume of the periodical
112
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
1-8
UT code for WoS article
000298403700001
EID of the result in the Scopus database
—