Pathogenetic Mechanisms of Neurogenic Pulmonary Edema
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F15%3A00446969" target="_blank" >RIV/67985823:_____/15:00446969 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1089/neu.2014.3609" target="_blank" >http://dx.doi.org/10.1089/neu.2014.3609</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1089/neu.2014.3609" target="_blank" >10.1089/neu.2014.3609</a>
Alternative languages
Result language
angličtina
Original language name
Pathogenetic Mechanisms of Neurogenic Pulmonary Edema
Original language description
Neurogenic pulmonary edema (NPE) is a life-threatening complication of central nervous system (CNS) injuries. NPE may develop as a result of activation of specific CNS trigger zones located in the brainstem, leading to a rapid sympathetic discharge, risein systemic blood pressure, baroreflex-induced bradycardia, and enhanced venous return resulting in pulmonary vascular congestion characterized by interstitial edema, intra-alveolar accumulation of transudate, and intra-alveolar hemorrhages. Degree of anesthesia is a crucial determinant for the extent of NPE development in experimental models because of its influence on sympathetic nervous system activity. Attenuation of sympathetic nerve activity or abolition of reflex bradycardia completely prevent NPE development in our experimental model
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GAP304%2F12%2F0259" target="_blank" >GAP304/12/0259: Mutual interactions of various vasoactive systems, reactive oxygen species and G proteins in experimental hypertension</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Neurotrauma
ISSN
0897-7151
e-ISSN
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Volume of the periodical
32
Issue of the periodical within the volume
15
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
1135-1145
UT code for WoS article
000363936800001
EID of the result in the Scopus database
2-s2.0-84936992953