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Pathogenetic Mechanisms of Neurogenic Pulmonary Edema

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F15%3A00446969" target="_blank" >RIV/67985823:_____/15:00446969 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1089/neu.2014.3609" target="_blank" >http://dx.doi.org/10.1089/neu.2014.3609</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1089/neu.2014.3609" target="_blank" >10.1089/neu.2014.3609</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Pathogenetic Mechanisms of Neurogenic Pulmonary Edema

  • Original language description

    Neurogenic pulmonary edema (NPE) is a life-threatening complication of central nervous system (CNS) injuries. NPE may develop as a result of activation of specific CNS trigger zones located in the brainstem, leading to a rapid sympathetic discharge, risein systemic blood pressure, baroreflex-induced bradycardia, and enhanced venous return resulting in pulmonary vascular congestion characterized by interstitial edema, intra-alveolar accumulation of transudate, and intra-alveolar hemorrhages. Degree of anesthesia is a crucial determinant for the extent of NPE development in experimental models because of its influence on sympathetic nervous system activity. Attenuation of sympathetic nerve activity or abolition of reflex bradycardia completely prevent NPE development in our experimental model

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    ED - Physiology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GAP304%2F12%2F0259" target="_blank" >GAP304/12/0259: Mutual interactions of various vasoactive systems, reactive oxygen species and G proteins in experimental hypertension</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Neurotrauma

  • ISSN

    0897-7151

  • e-ISSN

  • Volume of the periodical

    32

  • Issue of the periodical within the volume

    15

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    11

  • Pages from-to

    1135-1145

  • UT code for WoS article

    000363936800001

  • EID of the result in the Scopus database

    2-s2.0-84936992953