Upregulation of genes involved in cardiac metabolism enhances myocardial resistance to ischemia/reperfusion in the rat heart
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F13%3A00422631" target="_blank" >RIV/67985823:_____/13:00422631 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Upregulation of genes involved in cardiac metabolism enhances myocardial resistance to ischemia/reperfusion in the rat heart
Original language description
The results indicate that cardioprotection was associated with remarkably increased expression of PPAR-alpha target genes promoting FA utilization and reduced expression of glucose transporter GLUT-4. Potential non-genomic effects of PPAR-alpha-mediatedcardioprotection may involve activation of prosurvival PI3K/Akt pathway and its downstream targets such as eNOS and subsequently reduced apoptosis
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Result continuities
Project
<a href="/en/project/7AMB12SK164" target="_blank" >7AMB12SK164: The effect of lifestyle-related risk factors on the defensive mechanisms in the myocardium.</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Physiological Research
ISSN
0862-8408
e-ISSN
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Volume of the periodical
62
Issue of the periodical within the volume
Suppl.1
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
13
Pages from-to
"S151"-"S163"
UT code for WoS article
000328901900017
EID of the result in the Scopus database
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