Xenobiotic administration affects biotransformations of thyroid hormones in the rat

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F14%3A00432139" target="_blank" >RIV/67985823:_____/14:00432139 - isvavai.cz</a>
Result on the web
—
DOI - Digital Object Identifier
—

Result language
angličtina
Original language name
Xenobiotic administration affects biotransformations of thyroid hormones in the rat
Original language description
With the use of our newly developed radiometric enzyme assays for the determination of enzyme activities of iodothyronine deiodinases (IDs) of the types D1, D2 and D3, and adapted radiometric assays for quantification of iodothyronine sulfotransferases (ST) and uridine 5-diphospho glucuronyltransferase (UDP-GT), we proved thyrotoxic effects of excessive exogenous bromide and perchlorate ions. Profound changes in enzyme activities were also determined in rats treated with an antidepressant drug fluoxetine (Fluox), especially in case of IDs in their pituitary and cerebellum
Czech name
—
Czech description
—

Project
<a href="/en/project/7AMB14SK123" target="_blank" >7AMB14SK123: Investigation of the cardioprotection using n-3 PUFA against injury and malignant arrhythmias induced by altered thyroid status.</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Zborník príspevkov z medzinárodného vedeckého sympózia?Priemyslná toxikológia 2014?
ISBN
978-80-227-4181-1
ISSN
—
e-ISSN
—
Number of pages
7
Pages from-to
109-115
Publisher name
Slovenská technická univerzita
Place of publication
Bratislava
Event location
Svit, Vysoké Tatry
Event date
Jun 18, 2014
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
—

Similar results(10)