The effect of dynasore, a blocker of dynamin-dependent endocytosis, on spontaneous quantal and non-quantal release of acetylcholine in murine neuromuscular junctions

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F14%3A00444255" target="_blank" >RIV/67985823:_____/14:00444255 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1134/S0012496614060052" target="_blank" >http://dx.doi.org/10.1134/S0012496614060052</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1134/S0012496614060052" target="_blank" >10.1134/S0012496614060052</a>

Result language
angličtina
Original language name
The effect of dynasore, a blocker of dynamin-dependent endocytosis, on spontaneous quantal and non-quantal release of acetylcholine in murine neuromuscular junctions
Original language description
The hypothesis was tested that increase in spontaneous quantal secretion of ACh at neuromuscular synapse is accompanied by inhibition of the non-quantal release of the ACh because the rate of the vesicular endocytosis might be also increased. This ultimately restrains the number of ACh transporters integrated into the presynaptic membrane. After application of an inhibitor of endocytosis, dynasore, the non-quantal ACh release was not potentiated and the role of endocytosis in this process remains uncertain
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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