Preserved cardiac mitochondrial function and reduced ischaemia/reperfusion injury afforded by chronic continuous hypoxia: Role of opioid receptors

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F15%3A00444243" target="_blank" >RIV/67985823:_____/15:00444243 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1111/1440-1681.12383" target="_blank" >http://dx.doi.org/10.1111/1440-1681.12383</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/1440-1681.12383" target="_blank" >10.1111/1440-1681.12383</a>

Result language
angličtina
Original language name
Preserved cardiac mitochondrial function and reduced ischaemia/reperfusion injury afforded by chronic continuous hypoxia: Role of opioid receptors
Original language description
Adaptation of rats to chronic continuous hypoxia protected their hearts against post-ischemic contractile dysfunction, decreased creatine kinase release and attenuated the depression of mitochondrial respiration and calcium retention capacity. All thesebeneficial effects were abolished by naloxone. It suggests that the preserved mitochondrial function contributes to the protected cardiac phenotype conferred by chronic hypoxia and points to an important role of opioid receptor activation
Czech name
—
Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
—

Project
<a href="/en/project/GAP303%2F12%2F1162" target="_blank" >GAP303/12/1162: Interaction between sustained forms of cardioprotection induced by adaptation to chronic hypoxia and regular exercise training.</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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