RADIOMETRIC DETERMINATION OF THYROTOXIC EFFECTS OF SOME XENOBIOTICS

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F15%3A00472832" target="_blank" >RIV/67985823:_____/15:00472832 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/15:00116081
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
RADIOMETRIC DETERMINATION OF THYROTOXIC EFFECTS OF SOME XENOBIOTICS
Original language description
Recently, we have shown in the isolated rat thyroid glands marked effects of excessive exogenous bromide and perchlorate ions on the activity of thyroid peroxidase (TPO), the key enzyme in thyroid hormones (TH) metabolism. Here, we studied in more details effects of an enhanced bromide and/or perchlorate intake on various aspects of iodine metabolism and, consequently, on TH metabolism in the rat. With the use of several radioanalytical methods, including adapted radiometric determination of TPO enzyme activity, we confirmed and quantified the presumed thyrotoxic effects of xenobiotics bromide and perchlorate ions.
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
RAD 2015: THE THIRD INTERNATIONAL CONFERENCE ON RADIATION AND APPLICATIONS IN VARIOUS FIELDS OF RESEARCH
ISBN
978-86-80300-01-6
ISSN
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e-ISSN
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Number of pages
4
Pages from-to
463-466
Publisher name
RAD ASSOC
Place of publication
Niš
Event location
Budva
Event date
Jun 8, 2015
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000387979700096

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