Nanostructured materials as substrates for the adhesion, growth, and osteogenic differentiation of bone cells

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F16%3A00458563" target="_blank" >RIV/67985823:_____/16:00458563 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1016/B978-0-323-42862-0.00004-3" target="_blank" >http://dx.doi.org/10.1016/B978-0-323-42862-0.00004-3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/B978-0-323-42862-0.00004-3" target="_blank" >10.1016/B978-0-323-42862-0.00004-3</a>

Result language

angličtina

Original language name

Nanostructured materials as substrates for the adhesion, growth, and osteogenic differentiation of bone cells

Original language description

Nanostructured materials, particularly those with hierarchically organized macro-, micro-, and nanostructure, imitating the architecture of the natural bone tissue, are promising materials for construction of bone implants and bone tissue engineering. The nanoscale surface roughness has been unambiguously considered as a factor positively influencing the adhesion, growth, and phenotypic maturation of cells. The explanation is that the nanosized irregularities on a material surface mimic the nanoscale architecture of the native ECM. Materials already used or developed for bone implantation and bone tissue engineering can be divided into two basic groups: materials interacting with cells only on their surface, referred as two-dimensional (2D) materials, and materials enabling the ingrowth of cell into their inner structure, referred as three-dimensional (3D) materials. On 2D surfaces, the nanoscale features can be achieved by two main types of modification: subtractive and additive. Both technologies have been often combined. In 3D materials, nanostructure can be achieved by, for example, reinforcing macro- or microporous and micro- or nanofibrous polymeric scaffolds with ceramic, carbon-based, metal-based, or other nanoparticles. In this chapter, we summarize our experience and the experience of other authors concerning the adhesion, growth, and differentiation of osteogenic cells on 2D and 3D materials containing nanoscale features created by various technologies.

Czech name

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Czech description

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Type

C - Chapter in a specialist book

CEP classification

EI - Biotechnology and bionics

OECD FORD branch

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Project

<a href="/en/project/GBP108%2F12%2FG108" target="_blank" >GBP108/12/G108: Preparation, modification and characterization of materials by radiation</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Book/collection name

Nanobiomaterials in Hard Tissue Engineering

ISBN

978-0-323-42862-0

Number of pages of the result

51

Pages from-to

103-153

Number of pages of the book

484

Publisher name

Elsevier

Place of publication

Amsterdam

UT code for WoS chapter

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