The Regulatory Role of Nuclear Factor Kappa B in the Heart of Hereditary Hypertriglyceridemic Rat

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F16%3A00459551" target="_blank" >RIV/67985823:_____/16:00459551 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1155/2016/9814038" target="_blank" >http://dx.doi.org/10.1155/2016/9814038</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2016/9814038" target="_blank" >10.1155/2016/9814038</a>

Result language
angličtina
Original language name
The Regulatory Role of Nuclear Factor Kappa B in the Heart of Hereditary Hypertriglyceridemic Rat
Original language description
Activation of nuclear factor-kB by increased production of reactive oxygen species (ROS) might induce expression of different antioxidant enzymes and nitric oxide synthase (NOS) isoforms. NF-kB inhibition in hereditary hypertriglyceridemic rats led to decreased ROS degradation by superoxide dismutase and to increased cardiac oxidative damage and elevated blood pressure. Under these conditions increased NO generation may represent a counterregulatory mechanism activate by ROS.
Czech name
—
Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Project
<a href="/en/project/NV15-25396A" target="_blank" >NV15-25396A: Central and peripheral modulation of vascular tone and sodium excretion: the role of brain and kidney in pathophysiology of hypertension</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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