Decellularized Porcine Pericardium for Cardiovascular Tissue Engineering
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F16%3A00471889" target="_blank" >RIV/67985823:_____/16:00471889 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21460/16:00310150 RIV/68407700:21460/16:00310807 RIV/00023001:_____/16:00060169
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Decellularized Porcine Pericardium for Cardiovascular Tissue Engineering
Original language description
Biological prostheses made of decellularized cross-linked bovine pericardium and porcine aortic heart valves or mechanical prostheses are used for transplantation of aortic heart valves. None of these prostheses contain autologous cells. The purpose of our study is to prepare decellularized porcine pericardium, which would be suitable for colonizing with both autologous stem cells and endothelial cells, and subsequently transplanted into a patient. For decellularization, we tested different solutions and time of exposure. Effectiveness of decellularization process was assessed by hematoxylin-eosin staining and Hoechst staining. Extracts of the decellularized pericardium were evaluated for biocompatibility using xCelligence method. Decellularized porcine pericardium seems to be a suitable scaffold for preparing bioartificial heart valves.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
FA - Cardiovascular diseases including cardio-surgery
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
CORONARY ARTERY DISEASE 2015
ISBN
978-88-7587-729-3
ISSN
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e-ISSN
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Number of pages
4
Pages from-to
13-16
Publisher name
Medimond
Place of publication
Bologna
Event location
Florence
Event date
Nov 29, 2015
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000391237200003