Identification of short-chain poly-3-hydroxybutyrates in Saiga horn extracts using LC-MS/MS

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F19%3A00504500" target="_blank" >RIV/67985823:_____/19:00504500 - isvavai.cz</a>

Alternative codes found

RIV/00216275:25310/19:39915941

Result on the web

<a href="https://doi.org/10.1002/jssc.201800910" target="_blank" >https://doi.org/10.1002/jssc.201800910</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/jssc.201800910" target="_blank" >10.1002/jssc.201800910</a>

Result language

angličtina

Original language name

Identification of short-chain poly-3-hydroxybutyrates in Saiga horn extracts using LC-MS/MS

Original language description

Saiga horn extracts were analyzed with the goal of obtaining new information about compounds present in it. The purpose of this study is to find synthetic alternatives to Saiga horn extract, which is used in traditional Chinese medicine, by identifying potentially biologically active compounds in the extracts. Using high‐performance liquid chromatography coupled with high‐resolution mass spectrometry, we have been able to identify a series of short‐chain polyhydroxybutyrates in alcoholic extracts of Saiga horn. Optimized high‐performance liquid chromatography coupled with tandem mass spectrometry methods for analysis of short‐chain poly‐3‐hydroxybutyrates were developed and subsequently applied to investigate Saiga horn extract for the presence of these compounds, which might explain its biological actions, particularly for its antipyretic and procoagulant properties.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10406 - Analytical chemistry

Project

<a href="/en/project/GA17-10832S" target="_blank" >GA17-10832S: Advanced instrumentation and methodology for separation, analysis and characterization of (bio)moleclues by capillary electromigration methods.</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Separation Science

ISSN

1615-9306

e-ISSN

—

Volume of the periodical

42

Issue of the periodical within the volume

4

Country of publishing house

DE - GERMANY

Number of pages

12

Pages from-to

797-808

UT code for WoS article

000459327100002

EID of the result in the Scopus database

2-s2.0-85060336752