The role of interictal discharges in ictogenesis-A dynamical perspective

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F21%3A00544569" target="_blank" >RIV/67985823:_____/21:00544569 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/21:10429891

Result on the web

<a href="https://doi.org/10.1016/j.yebeh.2019.106591" target="_blank" >https://doi.org/10.1016/j.yebeh.2019.106591</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.yebeh.2019.106591" target="_blank" >10.1016/j.yebeh.2019.106591</a>

Result language

angličtina

Original language name

The role of interictal discharges in ictogenesis-A dynamical perspective

Original language description

Interictal epileptiform discharge (IED) is a traditional hallmark of epileptic tissue that is generated by the synchronous activity of a population of neurons. Interictal epileptiform discharges represent a heterogeneous group of pathological activities that differ in shape, duration, spatiotemporal distribution, underlying cellular and network mechanisms, and their relationship to seizure genesis. The exact role of IEDs in epilepsy is still not well understood, and there remains a persistent dichotomy about the impact on IEDs on seizures. Proseizure, antiseizure, and no impact on ictogenesis have all been described in previous studies. In this article, we review the existing knowledge on the role of interictal discharges in seizure genesis, and we discuss how dynamical approaches to ictogenesis can explain the existing dichotomy about the multifaceted role of IEDs in ictogenesis.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

<a href="/en/project/NV17-28427A" target="_blank" >NV17-28427A: Functional and structural reorganization of brain networks after stroke: implications for diagnosis and therapy of associated comorbidities.</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Epilepsy and Behavior

ISSN

1525-5050

e-ISSN

1525-5069

Volume of the periodical

121

Issue of the periodical within the volume

Part B Aug

Country of publishing house

US - UNITED STATES

Number of pages

6

Pages from-to

106591

UT code for WoS article

000674093100008

EID of the result in the Scopus database

2-s2.0-85076222299