Bone marrow adipose tissue: Role in bone remodeling and energy metabolism
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F21%3A00547572" target="_blank" >RIV/67985823:_____/21:00547572 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1016/j.beem.2021.101545" target="_blank" >https://doi.org/10.1016/j.beem.2021.101545</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.beem.2021.101545" target="_blank" >10.1016/j.beem.2021.101545</a>
Alternative languages
Result language
angličtina
Original language name
Bone marrow adipose tissue: Role in bone remodeling and energy metabolism
Original language description
Bone marrow adipose tissue (BMAT) has been considered for several decades as a silent bystander that fills empty space left in bone marrow following age-related decrease in hematopoiesis. However, recently new discoveries revealed BMAT as a secretory and metabolically active organ contributing to bone and whole-body energy metabolism. BMAT exhibits metabolic functions distinct from extramedullary adipose depots, relevant to its role in regulation of energy metabolism and its contribution to fracture risk observed in metabolic bone diseases. This review discusses novel insights of BMAT with particular emphasis on its contribution to the regulation of bone homeostasis. We also discuss the role of BMAT in regulation of fuel utilization and energy use that affect skeletal stem cell functions.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10601 - Cell biology
Result continuities
Project
<a href="/en/project/GA20-03586S" target="_blank" >GA20-03586S: Bone marrow adipose tissue (BMAT) as a novel adipose depot in the regulation of the whole body metabolism and bone homeostasis.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Best Practice & Research Clinical Endocrinology & Metabolism
ISSN
1521-690X
e-ISSN
1532-1908
Volume of the periodical
35
Issue of the periodical within the volume
4
Country of publishing house
GB - UNITED KINGDOM
Number of pages
15
Pages from-to
101545
UT code for WoS article
000709270900008
EID of the result in the Scopus database
2-s2.0-85107042727