Distinct retinal ganglion cell types in strictly subterranean, naturally microphthalmic mammals
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F25%3A00605155" target="_blank" >RIV/67985823:_____/25:00605155 - isvavai.cz</a>
Alternative codes found
RIV/68378050:_____/25:00645612 RIV/00216208:11310/25:10508230 RIV/60460709:41320/25:102942
Result on the web
<a href="https://doi.org/10.1098/rspb.2024.2586" target="_blank" >https://doi.org/10.1098/rspb.2024.2586</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1098/rspb.2024.2586" target="_blank" >10.1098/rspb.2024.2586</a>
Alternative languages
Result language
angličtina
Original language name
Distinct retinal ganglion cell types in strictly subterranean, naturally microphthalmic mammals
Original language description
African mole-rats (Bathyergidae, Rodentia) are subterranean rodents that live in extensive dark underground tunnel systems and rarely emerge aboveground. They can discriminate between light and dark but show no overt visually driven behaviours except for light-avoidance responses. Their eyes and central visual system are strongly reduced but not degenerated. Here, we focus on retinal ganglion cells (RGCs). Sighted mammals have numerous RGC types with distinct morphological and functional properties that encode different aspects of a visual scene. We analysed the morphological diversity of 216 intracellularly dye-injected RGCs in the giant mole-rat (Fukomys mechowii) and 48 RGCs in Ansell's mole-rat (Fukomys anselli). Using a hierarchical cluster analysis on 11 morphological parameters, we show that both species possess at least five RGC types with distinct dendritic field sizes and branching patterns. These resemble some RGC types of the mouse and rat, but mole-rat RGCs feature overall sparser and more asymmetric branching patterns. The dendritic trees of most RGCs in all clusters are monostratified in the inner plexiform layer, but bistratified and multistratified/diffuse cells also exist. Thus, although RGC morphologies have become disorganized, the basic retinal organization principle of parallel information processing by distinct RGC types is retained.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
Result continuities
Project
<a href="/en/project/GA22-35153S" target="_blank" >GA22-35153S: Number of Neurons in Avian Brains: Implications for Evolution of Bird Intelligence</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Proceedings of the Royal Society B-Biological Sciences
ISSN
0962-8452
e-ISSN
1471-2954
Volume of the periodical
292
Issue of the periodical within the volume
2038
Country of publishing house
GB - UNITED KINGDOM
Number of pages
12
Pages from-to
20242586
UT code for WoS article
001397283800011
EID of the result in the Scopus database
2-s2.0-85215758885