Development of Separation Methods for the Chiral Resolution of Hexahelicenes.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985858%3A_____%2F16%3A00472516" target="_blank" >RIV/67985858:_____/16:00472516 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/16:10332097 RIV/61989592:15110/16:33161406 RIV/61989592:15310/16:33161406
Result on the web
<a href="http://dx.doi.org/10.1016/j.chroma.2016.10.083" target="_blank" >http://dx.doi.org/10.1016/j.chroma.2016.10.083</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.chroma.2016.10.083" target="_blank" >10.1016/j.chroma.2016.10.083</a>
Alternative languages
Result language
angličtina
Original language name
Development of Separation Methods for the Chiral Resolution of Hexahelicenes.
Original language description
In this short communication we report optimized procedures for the chiral separation of non-charged [6]helicene (1) and cationic derivative 1-butyl-3-(2-methyl[6]helicenyl)-imidazolium bromide (2) using high-performance liquid chromatography (HPLC) and supercritical fluid chromatography (SFC) methods. The possibility of using capillary electrophoresis (CE) was also tested. The satisfactory results were obtained with SFC, where the highly selective resolution of four enantiopure 1 and 2 helicenes was achieved in a single run within 5 min. The semi-preparative procedure for the isolation of P and M enantiomers of compound 2, including circular dichroism data, is reported here for the first time. The results could be used in further separations and analytical applications targeting carbohelicenes vs. positively charged helicene derivatives.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Chromatography A
ISSN
0021-9673
e-ISSN
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Volume of the periodical
1476
Issue of the periodical within the volume
DEC 9
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
5
Pages from-to
130-134
UT code for WoS article
000390498500015
EID of the result in the Scopus database
2-s2.0-84998953911