Analytical Value of Detecting an Individual Molecular Binding Event:The Case of the Surface Plasmon Resonance Biosensor

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985882%3A_____%2F12%3A00374553" target="_blank" >RIV/67985882:_____/12:00374553 - isvavai.cz</a>

Alternative codes found

RIV/67985882:_____/12:00396900

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Analytical Value of Detecting an Individual Molecular Binding Event:The Case of the Surface Plasmon Resonance Biosensor

Original language description

In this study, we compare the bioanalytical performance of flow-through surface plasmon resonance (SPR) sensors based on (1) localized surface plasmons (LSP) which detect a single binding event and (2) propagating surface plasmons (PSP) which integrate agreat number of simultaneously occurring binding events. We demonstrate that for the biomolecular interactions most relevant to biosensing the LSP approach is inferior to the PSP approach due to low probability of positive sensor response.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

JB - Sensors, detecting elements, measurement and regulation

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Analytical Chemistry

ISSN

0003-2700

e-ISSN

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Volume of the periodical

84

Issue of the periodical within the volume

1

Country of publishing house

US - UNITED STATES

Number of pages

4

Pages from-to

30-34

UT code for WoS article

000298763900007

EID of the result in the Scopus database

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